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Updated: Jan 26, 2026

Metabolic Mapping: Quantitative Enzyme Cytochemistry and Histochemistry to Determine the Activity of Dehydrogenases in Cells and Tissues
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Effect of pterostilbene on in vitro drug metabolizing enzyme activity

Ahmed A Albassam1,2, Reginald F Frye2

  • 1Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.

Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society
|April 13, 2019
PubMed

Keywords:
AmodiaquineCYP, cytochrome P450CYP2C8DEAQ, desethylamodiaquineEnzyme inhibitionHIM, human intestine microsomesHLM, human liver microsomesHPLC, high-performance liquid chromatographyHydroxypioglitazoneIC50, concentration of inhibitor that results in 50% inhibition of reactionLC-MS/MS, liquid chromatography/tandem mass spectrometryM-IV, hydroxypioglitazoneN-desethylamodiaquinePioglitazonePterostilbeneRDI, recommended daily intakeSerotoninSerotonin glucuronideUDPGA, uridine diphosphate glucuronic acidUGT, UDP-glucuronosyltransferaseUGT1A6V/D, volume per dose index

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