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B-cell central nervous system lymphoma developing in a patient with cerebral meningioangiomatosis

Salvatore Stilo1, Lorenzo Ugga1, Camilla Russo1

  • 1Department of Advanced Biomedical Sciences, Neuroradiology Unit, University "Federico II", Via Pansini, 5, 80131 Naples, Italy.

Radiology Case Reports
|April 13, 2019
PubMed

Insights

Meningioangiomatosis, a rare congenital malformation, was observed in a patient before the development of central nervous system B-cell lymphoma. This case highlights the potential for meningioangiomatosis to be associated with other pathologies more often than previously recognized.

Area of Science:

  • Neurology
  • Pathology
  • Medical Imaging

Background:

  • Meningioangiomatosis is a rare congenital hamartomatous malformation affecting the leptomeninges and adjacent brain tissue.
  • It is occasionally associated with neurofibromatosis.

Observation:

  • A 55-year-old man presented with neuroradiological evidence of meningioangiomatosis.
  • This lesion preceded the development of central nervous system B-cell lymphoma.

Findings:

  • This report details the first documented case of meningioangiomatosis preceding central nervous system B-cell lymphoma.
  • The findings suggest meningioangiomatosis may be associated with other pathologies more often than previously recognized.

Implications:

  • This association expands the known clinical spectrum of meningioangiomatosis.
  • Further research is warranted to explore the potential link between meningioangiomatosis and lymphoproliferative disorders.
Keywords:
LymphomaMagnetic resonance imagingMeningioangiomatosisNeurofibromatosis

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