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Fatigue, depression, and quality of life in children with multiple sclerosis: a comparative study with other

Anca Florea1, Helene Maurey1, Melanie Le Sauter1

  • 1Pediatric Neurology Department, National Referral Center for Rare Inflammatory Brain and Spinal Diseases, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Hôpitaux Universitaires Paris-Sud, Le Kremlin Bicêtre, France.

Developmental Medicine and Child Neurology
|April 13, 2019
PubMed

Insights

Children with pediatric multiple sclerosis experience significant fatigue and depression, impacting emotional and school functioning. These invisible symptoms require careful consideration in treatment plans for improved quality of life.

Area of Science:

  • Pediatric Neurology
  • Neuroimmunology
  • Child Psychology

Background:

  • Multiple Sclerosis (MS) and Acute Demyelinating Syndromes (ADS) can affect children.
  • Understanding the impact of these conditions on children's well-being is crucial for effective management.

Purpose of the Study:

  • To evaluate fatigue, depression, and quality of life (QoL) in children diagnosed with MS.
  • To compare these outcomes with children experiencing other forms of ADS.

Main Methods:

  • A cohort of children from a national referral center for rare inflammatory brain diseases was studied.
  • Standardized scales were used to assess disability, fatigue, depression, and QoL.

Main Results:

  • While not statistically significant, fatigue was reported less in MS patients (44%) than ADS patients (63%).
  • Depression was more prevalent in the MS group (24%) compared to the ADS group (18%).
  • Children with MS reported poor emotional and school functioning, while physical and social functioning were rated higher.

Conclusions:

  • Fatigue and depression are significant concerns in pediatric MS and ADS.
  • Emotional and academic functioning are key areas of concern for children with MS and their families, necessitating tailored care.
  • Addressing these 'invisible' symptoms is vital for comprehensive pediatric MS and ADS management.
Abstract

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