Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

7.9K
Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
7.9K
Patch Clamp01:18

Patch Clamp

6.4K
Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
6.4K
Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

19.7K
The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...
19.7K
The Scientific Method01:32

The Scientific Method

261.4K
The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
261.4K
Protein Complex Assembly02:41

Protein Complex Assembly

16.7K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
16.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Topical Melatonin in Aesthetic Dermatology: From Cutaneous Melatoninergic Biology to Photoprotection, and Skin Rejuvenation.

Clinics in dermatology·2026
Same author

Deep Learning vs. Traditional Machine Learning in the Diagnosis of Cutaneous Drug Eruptions: A Comparative Study with Explainable AI on Whole-Slide Images.

Journal of imaging informatics in medicine·2026
Same author

Occupational Risk of Sexually Transmitted Infections in Aesthetic Dermatology and Dermatologic Surgery: Evidence and Prevention.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
Same author

Sleep quality in patients with mycosis fungoides and its relationship with dermatology-specific quality of life.

Clinics in dermatology·2026
Same author

Age-related histopathological and immunophenotypic variations in early-stage mycosis fungoides: a multicentre retrospective study in Türkiye.

BMJ open·2026
Same author

Persona non grata: Identifying patients unsuitable for aesthetic dermatologic procedures.

Clinics in dermatology·2026

Related Experiment Video

Updated: Jan 26, 2026

Transdermal Measurement of Glomerular Filtration Rate in Mice
07:25

Transdermal Measurement of Glomerular Filtration Rate in Mice

Published on: October 21, 2018

23.3K

Transdermal patches in dermatology.

Begüm Ünlü1, Ümit Türsen1

  • 1Department of Dermatology, School of Medicine, Mersin University, Mersin, Turkey.

Dermatologic Therapy
|April 13, 2019
PubMed
Summary

Transdermal patches offer effective drug delivery by absorbing medication through the skin into the bloodstream. This method bypasses liver metabolism, ensuring stable drug levels and reducing interactions for convenient treatment.

Keywords:
capsaicindermatologydissolving microneedlehyaluronic acidtransdermal patches

More Related Videos

Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets
07:41

Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets

Published on: September 13, 2022

3.6K
One-channel Cell-attached Patch-clamp Recording
13:07

One-channel Cell-attached Patch-clamp Recording

Published on: June 9, 2014

25.4K

Related Experiment Videos

Last Updated: Jan 26, 2026

Transdermal Measurement of Glomerular Filtration Rate in Mice
07:25

Transdermal Measurement of Glomerular Filtration Rate in Mice

Published on: October 21, 2018

23.3K
Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets
07:41

Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets

Published on: September 13, 2022

3.6K
One-channel Cell-attached Patch-clamp Recording
13:07

One-channel Cell-attached Patch-clamp Recording

Published on: June 9, 2014

25.4K

Area of Science:

  • Dermatology
  • Pharmacology
  • Drug Delivery Systems

Background:

  • Transdermal patches represent an advanced drug delivery system with numerous benefits.
  • This method involves the absorption of active ingredients through the skin into the capillaries, reaching systemic circulation.

Purpose of the Study:

  • To highlight the advantages of transdermal patch technology.
  • To underscore the clinical utility and convenience of transdermal drug delivery.

Main Methods:

  • Review of transdermal patch mechanisms.
  • Analysis of pharmacokinetic and pharmacodynamic benefits.
  • Discussion of clinical applications in dermatology.

Main Results:

  • Transdermal patches bypass hepatic first-pass metabolism.
  • Consistent and prolonged drug plasma levels are achieved.
  • Reduced potential for drug-drug interactions and improved patient compliance.

Conclusions:

  • Transdermal patches offer a practical and effective route for drug administration.
  • Their ability to maintain stable drug levels and minimize interactions makes them valuable in various dermatological treatments.