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Blood coagulation dynamic testing sensor based on electromagnetic vibration.

Zhe Wang1, Yuan-Hua Yu1,2, Zhan-Jiang Yu1,3

  • 11 Changchun University of Science and Technology, Changchun, China.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
|April 13, 2019
PubMed
Summary
This summary is machine-generated.

A new electromagnetic induction sensor offers rapid, accurate blood coagulation testing at the point-of-care. This technology meets clinical accuracy needs and supports development of new diagnostic instruments.

Keywords:
Sensorblood coagulation dynamic testingdynamics modelingelastic supportelectromagnetic vibration

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Analytical Chemistry

Background:

  • Growing demand for rapid blood coagulation assessment in clinical settings, particularly for point-of-care testing (POCT).
  • Existing methods may lack the speed or accuracy required for immediate patient management in critical care.

Purpose of the Study:

  • To develop and validate a novel electromagnetic induction-based sensor for rapid blood coagulation detection.
  • To establish the core technology for a new generation of POCT instruments for dynamic coagulation testing.

Main Methods:

  • Established a dynamics model of the vibration system using damping vibration principles.
  • Performed harmonic response and vibration fatigue coupling analyses, optimizing results.
  • Constructed an experimental electromagnetic induction testing sensor and integrated it with coagulation reagents for POCT.

Main Results:

  • The designed sensor exhibited a first-order natural frequency of 102.35 Hz.
  • High correlation (0.996) with imported POCT equipment was achieved.
  • Excellent testing repeatability (0.002) was demonstrated, meeting clinical accuracy requirements.

Conclusions:

  • The developed electromagnetic induction sensor possesses favorable elasticity and anti-fatigue properties.
  • This sensor technology is suitable for accurate, rapid clinical blood coagulation detection.
  • The study provides foundational technology for advancing POCT devices for coagulation monitoring.