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Related Concept Videos

Colloids03:22

Colloids

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Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
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Colloids and Suspensions01:17

Colloids and Suspensions

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Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles visible to the naked eye or seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. The suspended particles in a suspension settle out after some time of mixing. The separation of particles from a suspension is...
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Colloidal precipitates01:09

Colloidal precipitates

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The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
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Uncertainty in Measurement: Reading Instruments02:46

Uncertainty in Measurement: Reading Instruments

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Counting is the type of measurement that is free from uncertainty, provided the number of objects being counted does not change during the process. Such measurements result in exact numbers. By counting the eggs in a carton, for instance, one can determine exactly how many eggs are there in the carton. Similarly, the numbers of defined quantities are also exact. For example, 1 foot is exactly 12 inches, 1 inch is exactly 2.54 centimeters, and 1 gram is exactly 0.001 kilograms. Quantities...
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Instrument Transformers01:23

Instrument Transformers

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Instrument transformers, comprising voltage transformers (VTs) and current transformers (CTs), play crucial roles in power substations by providing isolated replicas of current or voltage for measurement and protection purposes. Voltage transformers reduce the primary voltage to levels suitable for relay operation and measurement, while current transformers scale down the primary current. The primary winding of a current transformer often consists of a single turn, achieved by threading the...
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Instrument Calibration01:12

Instrument Calibration

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Instrument calibration is essential for ensuring that instruments produce accurate and consistent results. It is vital in manufacturing, healthcare, testing laboratories, and scientific research. Calibration processes are specific to each instrument and help enhance data accuracy. Each instrument has a unique calibration process tailored to its design and function to improve data accuracy.
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Related Experiment Video

Updated: Jan 26, 2026

Development of a Colloidal Gold-based Immunochromatographic Test Strip for Detection of Cetacean Myoglobin
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[Development of Colloidal Gold Detector Instrument Based on CMOS Image Processing].

Lei Wang1, Zhichao Duan1

  • 1Tianjin Paipudaye Instrument Technology Co Ltd, Tianjin, 300400.

Zhongguo Yi Liao Qi Xie Za Zhi = Chinese Journal of Medical Instrumentation
|April 13, 2019
PubMed
Summary

This study presents a novel immune colloidal gold detector for versatile testing. The instrument demonstrates high accuracy and repeatability in quantitative C-reactive protein analysis.

Keywords:
CMOS image sensorcolloidal goldquantitative test

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Immunotechnology

Background:

  • Immune colloidal gold assays are widely used for rapid diagnostics.
  • Existing instruments may lack versatility and automated parameter adjustment.
  • There is a need for robust and adaptable detection platforms.

Purpose of the Study:

  • To develop and validate a novel immune colloidal gold detector instrument.
  • To assess the instrument's performance in quantitative analysis.
  • To demonstrate its applicability across various test items.

Main Methods:

  • The instrument integrates machinery, hardware, and software components.
  • Image acquisition is performed using a CMOS sensor.
  • Image processing algorithms on a Linux platform analyze the data, with adjustable parameters for different assays.

Main Results:

  • Quantitative testing of C-reactive protein samples yielded a coefficient of determination (R²) of 0.99.
  • The instrument demonstrated excellent repeatability, exceeding 93%.
  • The system's design allows for flexible application to diverse analytes.

Conclusions:

  • The developed immune colloidal gold detector is accurate, repeatable, and versatile.
  • The instrument's automated parameter setting enhances its utility for various diagnostic applications.
  • This technology holds promise for improved point-of-care testing and laboratory diagnostics.