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Updated: Jan 26, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
Late adult-onset epilepsy in a patient with hemimegalencephaly
Seth A Climans1, Seyed M Mirsattari1
1Departments of Clinical Neurological Sciences (SAC, SMM), Medical Imaging (SMM), Medical Biophysics (SMM), Psychology (SMM), Western University, London, Canada.
Abstract:
Hemimegalencephaly is a malformation of cortical development that normally manifests in childhood with seizures and cognitive impairment. We present a case of hemimegalencephaly in a 55-year-old developmentally-normal woman who developed focal impaired awareness seizures with bilateral tonic-clonic spread. Her interictal EEG showed left-sided multifocal spikes, and ictal EEG showed seizures starting in the left hemisphere. Imaging showed hemimegalencephaly. This case may represent the oldest age for a first seizure in a patient with hemimegalencephaly.
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