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Partial Bile Duct Ligation in the Mouse: A Controlled Model of Localized Obstructive Cholestasis
Published on: March 28, 2018
[Cytomegalovirus cholestasis in an immunocompetent host]
Ali Ouandaf1, Hasna Chergui2, Meriem Seffar1
1Université Mohammed V, Faculté de médecine et de pharmacie de Rabat, Centre Hospitalier Universitaire Ibn Sina, Hôpital des spécialités, Laboratoire central de virologie, Rabat, Maroc.
Abstract:
Primary infection or reactivation of cytomegalovirus (CMV) can induce in immunocompromised patients a severe disease depending on the type of immuno-suppression, and can affect multiple organs. On the other hand, the infection is benign and mostly asymptomatic in immunocompetent individuals who do not require antiviral treatment. Rare cases of primary infection have been documented. In this article, we report the case of a 21-year-old immunocompetent female patient with CMV cholestatic jaundice. The diagnosis was retained on all clinico-pathologic data after eliminating the autoimmune, surgical and other infectious causes. Resolution of cholestasis has been observed with ganciclovir.
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