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Updated: Jan 26, 2026

Bovine Mammary Gland Biopsy Techniques
Published on: December 23, 2018
Antiviral Substances in Raw Bovine Milk Active Against Bovine Rotavirus and Coronavirus
Abstract:
After experimental contamination of bovine raw and heat-treated milks with bovine rotavirus and coronavirus strains, we observed a strong viral inhibition only with raw milks, from which virus recovery was 5 × 10-4%. Between 30% and 80% of the virus was recovered from the heat-treated milks, depending on the level of inoculation. The antiviral substance is heat-labile (destroyed within 30 min at 100°C), precipitated by ammonium sulfate and filtrable (0.45 μm Millipore membrane). It also has neutralizing activity on tissue culture.
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