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Antibiotic/Antimicrobial Residues in Milk 1.

M S Brady1, S E Katz1

  • 1Department of Biochemistry and Microbiology, Cook College, New Jersey Agricultural Experiment Station, Rutgers - The State University of New Jersey, New Brunswick, New Jersey 08903.

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Most milk samples contained antibiotic residues, with tetracyclines and sulfonamides being most common. This study surveyed milk quality in the Pennsylvania, New Jersey, and New York City area.

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Area of Science:

  • Food safety
  • Analytical chemistry
  • Microbiology

Background:

  • Antibiotic and antimicrobial residues in milk pose a potential public health risk.
  • Monitoring milk for these residues is crucial for ensuring consumer safety.
  • Previous surveys have indicated the presence of residues, but regional data is valuable.

Purpose of the Study:

  • To assess the prevalence of antibiotic and antimicrobial residues in commercially available milk.
  • To identify the types of residues most frequently detected in the surveyed region.
  • To validate qualitative findings with confirmatory microbial assays.

Main Methods:

  • A qualitative receptor assay was employed to screen commercial milk samples.
  • Samples were collected over a 3-month period from various brands and bottling plants in the eastern Pennsylvania, Central New Jersey, and New York City area.
  • Presumptive positive samples were further analyzed using microbial assays for confirmation.

Main Results:

  • 63% of the 64 milk samples tested contained one or more residues.
  • 27% of samples had two residues, and 11% had three or more.
  • Tetracyclines and sulfonamides were the most predominant residues detected.
  • Confirmatory assays confirmed 100% of presumptive tetracycline-positive samples and 75% of presumptive streptomycin-positive samples.

Conclusions:

  • A significant percentage of commercial milk in the surveyed region contains antibiotic and antimicrobial residues.
  • Tetracyclines and sulfonamides are the primary residues of concern.
  • The qualitative assay demonstrated good reliability when confirmed by microbial assays.