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Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
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Peptic Ulcer Disease II: Pathophysiology01:28

Peptic Ulcer Disease II: Pathophysiology

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Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
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Simplified Synchronous Machine Model01:30

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The Synchronous Machine Model is a fundamental tool in analyzing and ensuring the transient stability of power systems. This model simplifies the representation of a synchronous machine under balanced three-phase positive-sequence conditions, assuming constant excitation and ignoring losses and saturation. The model is pivotal for understanding the behavior of synchronous generators connected to a power grid, particularly during transient events.
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Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

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Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
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Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

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Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
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Acute Fulminant-Onset Synchronized CMV-Ulcerative Colitis.

Omer Burcak Binicier1, Sevil Ozer Sari1

  • 1Tepecik Education and Research Hospital, Department of Gastroenterology, Yenisehir-Izmir, Turkey.

Archives of Iranian Medicine
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Summary

Cytomegalovirus (CMV) infection can cause latent lifelong illness. This case study details a rare instance of simultaneous, severe CMV and ulcerative colitis onset in an otherwise healthy 58-year-old man.

Area of Science:

  • Virology
  • Gastroenterology
  • Immunology
Keywords:
CytomegalovirusFulminant ColitisUlcerative Colitis

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Background:

  • Cytomegalovirus (CMV) is a common virus causing asymptomatic, lifelong infections in most individuals.
  • Symptomatic CMV infections typically occur in immunocompromised patients, including organ transplant recipients, those on immunosuppressants, dialysis patients, and individuals with AIDS.
  • A connection between ulcerative colitis and CMV infection, along with the effectiveness of antiviral treatments, has been previously established.