Multiple Deeply Divergent Denisovan Ancestries in Papuans
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View abstract on PubMed
Summary
This summary is machine-generated.Modern humans interbred with multiple Denisovan groups, not just one. Ancient DNA analysis reveals distinct Denisovan lineages in Papuans and East Asians, indicating complex archaic hominin interactions.
Area Of Science
- Human Evolution
- Paleogenetics
- Population Genetics
Background
- Genome sequences of Neanderthals and Denisovans are known.
- Archaic hominins interbred with modern humans dispersing from Africa.
Purpose Of The Study
- To investigate archaic DNA in modern populations of Island Southeast Asia and New Guinea.
- To determine the origin and complexity of archaic hominin introgression.
Main Methods
- Analysis of 161 new genomes from Island Southeast Asia and New Guinea.
- Identification of high-confidence archaic haplotypes.
- Comparison with known archaic hominin genomes.
Main Results
- High-confidence archaic haplotypes were identified in 161 new genomes.
- Modern Papuans carry gene variants from two deeply divergent Denisovan lineages.
- A third Denisovan lineage was found in modern East Asians.
Conclusions
- Introgression involved multiple, geographically isolated Denisovan groups.
- Denisovan lineages separated over 350,000 years ago.
- Archaic hominin contact was complex, with regional variations.
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