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Related Experiment Videos

Growth and childhood asthma.

L Balfour-Lynn

    Archives of Disease in Childhood
    |November 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Children with chronic perennial asthma may experience delayed puberty, not growth retardation. Their growth eventually normalizes, reaching predicted adult height after puberty onset.

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    Area of Science:

    • Pediatric Endocrinology
    • Pulmonology
    • Growth and Development

    Background:

    • Chronic perennial asthma affects children's growth and development.
    • Understanding asthma's impact on pubertal timing is crucial for pediatric care.

    Purpose of the Study:

    • To investigate the long-term effects of chronic perennial asthma on children's growth and pubertal development.
    • To determine if asthma or its treatment influences growth velocity and final adult height.

    Main Methods:

    • Prospective longitudinal study of 66 children with chronic perennial asthma over a mean of 13.1 years.
    • Regular measurements of height and weight every six months.
    • Assessment of pubertal development, including onset and progression.

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    Main Results:

    • No evidence of growth retardation at study entry; growth followed normal patterns until approximately age 10.
    • A significant tendency for delayed puberty onset was observed in both boys and girls, independent of asthma severity.
    • Complete catch-up growth occurred after puberty onset, leading to attainment of predicted adult height.
    • Inhaled beclomethasone dipropionate did not affect growth in children treated before and during puberty.

    Conclusions:

    • Asthma is associated with a delay in the onset of puberty, not direct growth retardation.
    • The pre-adolescent deceleration in growth velocity in asthmatic children can mimic growth retardation.
    • Asthma management, including inhaled corticosteroids, does not appear to impede overall growth or final height attainment.