Related Experiment Video
Updated: Jan 26, 2026

Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure
Published on: June 5, 2020
Testing multiplicative terms in AMMI and GGE models for multienvironment trials with replicates
Waqas Ahmed Malik1, Johannes Forkman2, Hans-Peter Piepho3
1Biostatistics Unit, Institute of Crop Science, University of Hohenheim, Fruwirthstrasse 23, 70599, Stuttgart, Germany. w.malik@uni-hohenheim.de.
A new resampling method robustly tests multiplicative interactions in plant breeding trials. This approach for additive main effects and multiplicative interaction (AMMI) and genotype main effects and genotype-by-environment interaction (GGE) models outperforms existing methods, especially with varied variances.
Area of Science:
- Agricultural Science
- Biometrics
- Plant Breeding
Background:
- Additive Main Effects and Multiplicative Interaction (AMMI) and Genotype Main Effects and Genotype-by-Environment Interaction (GGE) models are standard for analyzing multienvironment trial data.
- Agronomists and plant breeders utilize these models for cultivar trials across diverse environments and years.
- Determining the number of significant multiplicative interaction terms is critical in these analyses.
Purpose of the Study:
- To propose a resampling-based method for testing the significance of multiplicative interaction terms in AMMI and GGE models.
- To offer a robust alternative to existing parametric tests that assume normality and homogeneous variance.
- To evaluate the performance of the proposed method against competing tests.
Main Methods:
- Development of resampling-based methods for analyzing multienvironment trial data with replicates.
- Comparison of proposed methods with existing parametric tests.
- Extensive simulation study using data from two multienvironment trials.
Main Results:
- The proposed resampling methods demonstrate robust performance in terms of Type-I error rates, irrespective of error distribution.
- The methods are superior to contending methods in robustness to heterogeneity of variance.
- The proposed method outperforms the robust t-test when normality and homogeneity of variance assumptions are violated.
Conclusions:
- Resampling-based methods provide a reliable approach for analyzing multienvironment trials with replicates.
- These methods offer improved robustness, particularly when standard statistical assumptions are not met.
- The findings support the adoption of resampling techniques for more accurate significance testing in plant breeding and agronomy.
More Related Videos
Related Concept Videos
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Replication in Eukaryotes
Chromosome Replication
DNA Replication
Replication in Prokaryotes
DNA replication...
Replication in Prokaryotes
The DNA Replication Fork

