Related Experiment Video
Updated: Jan 26, 2026
05:19
Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
10.7K
Validity and reliability of the reflux symptom score
Jérôme R Lechien1,2,3,4, Francois Bobin1,5, Vinciane Muls6
1Research Committee of the Young Otolaryngologists of the International Federation of Oto-Rhino-Laryngological Societies (YO-IFOS), Marseille, France.
The Laryngoscope
|April 16, 2019
Summary
The Reflux Symptom Score (RSS) is a reliable and valid self-administered questionnaire for diagnosing and monitoring laryngopharyngeal reflux (LPR). This tool aids in assessing LPR symptoms effectively.
Area of Science:
- Gastroenterology and Otolaryngology
- Patient-Reported Outcome Measures
- Diagnostic Tool Development
Background:
- Laryngopharyngeal reflux (LPR) presents diagnostic challenges.
- Validated patient-reported outcome measures are crucial for assessing LPR.
- Existing tools may not fully capture the symptom burden of LPR.
Purpose of the Study:
- To develop and validate the Reflux Symptom Score (RSS), a self-administered questionnaire for LPR.
- To establish the reliability and validity of the RSS in patients with LPR.
- To determine the responsiveness of the RSS to treatment.
Main Methods:
- Prospective controlled study involving 113 LPR patients and 80 controls.
- Assessed test-retest reliability and internal consistency (Cronbach's α) of the RSS.
- Evaluated validity against Reflux Symptom Index (RSI) and Voice Handicap Index (VHI), and responsiveness to treatment.
Main Results:
- The RSS demonstrated high test-retest reliability (rs = 0.921) and internal consistency (α = 0.969).
- RSS showed high external validity (rs = 0.831 with RSI) and internal validity (higher scores in patients vs. controls).
- RSS scores significantly improved with treatment, indicating responsiveness; RSS >13 suggests LPR symptoms.
Conclusions:
- The Reflux Symptom Score (RSS) is a reliable and valid self-administered tool for LPR.
- RSS demonstrates excellent criterion-based validity and responsiveness to treatment.
- The RSS can be effectively utilized for diagnosing and monitoring LPR disease.
More Related Videos
15:49Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
32.6K
04:33Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
1.3K
Related Concept Videos
01:29Reliability and Validity
13.8K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
13.8K
01:06Introduction to z Scores
11.0K
A z score (or standardized value) is measured in units of the standard deviation. It tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
z scores...
z scores...
11.0K
01:05Introduction to z Scores
1.3K
A z score (or standardized value) is measured in units of the standard deviation. It indicates how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
z scores...
z scores...
1.3K
01:17z Scores and Area Under the Curve
18.4K
z scores are the standardized values obtained after converting a normal distribution into a standard normal distribution. A z score is measured in units of the standard deviation. The z score tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a z score of...
18.4K
01:15Diabetes: Symptoms, Diagnosis, and Complications
2.1K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.1K
01:30Negative and Cognitive Symptoms of Schizophrenia
528
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
528