Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

199
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
199
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

203
Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
203
Gene Therapy00:59

Gene Therapy

27.4K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.4K
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

475
Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
475
Group Therapy01:26

Group Therapy

410
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
410
Psychodynamic Therapy01:29

Psychodynamic Therapy

545
Psychodynamic therapies emphasize the exploration of unconscious processes and early childhood experiences as fundamental contributors to psychological difficulties. These therapies, deeply rooted in Freud's psychoanalytic theory, aim to uncover and resolve unconscious conflicts, granting individuals insights that promote emotional and behavioral healing. Contemporary psychodynamic approaches have evolved, integrating a broader range of influences and methodologies while still valuing the...
545

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Obinutuzumab or Tacrolimus in Primary Membranous Nephropathy.

The New England journal of medicine·2026
Same author

Global Treatment Patterns for Immunoglobulin A Nephropathy in Adults: Results from a Real-World Survey.

Glomerular diseases·2026
Same author

Advancing Care in Lupus Nephritis: Expert Perspectives on Current Practices and Future Directions in Italy.

Journal of clinical medicine·2026
Same author

Unveiling the silent burden: high prevalence of occult nephropathies in radical nephrectomy specimens.

Clinical kidney journal·2026
Same author

Health Care Resource Utilization and Productivity Impairment in Adults with Immunoglobulin A Nephropathy: A Real-World, Observational, Global Analysis.

Glomerular diseases·2026
Same author

Regional Citrate Anticoagulation in CRRT: Successes, Pitfalls, and Sustainability from a Long-Term Single-Center Experience.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Jan 26, 2026

Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment
03:50

Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment

Published on: August 2, 2024

2.0K

[Extracorporeal therapy in sepsis].

Marco Pozzato1, Sergio Livigni2, Dario Roccatello1

  • 1Struttura Complessa Universitaria di Nefrologia e Dialisi - CMID, Ospedale San Giovanni Bosco, ASL Città di Torino, Torino.

Giornale Italiano Di Nefrologia : Organo Ufficiale Della Societa Italiana Di Nefrologia
|April 16, 2019
PubMed
Summary

Sepsis-associated acute kidney injury (AKI) is common and deadly. New research suggests AKI in sepsis results from complex interactions, not just low blood flow, highlighting the need for personalized treatments.

Keywords:
CPFACRRTS-AKIadsorptioncitrateseptic shock

More Related Videos

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
06:41

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Published on: October 24, 2018

13.0K
A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

487

Related Experiment Videos

Last Updated: Jan 26, 2026

Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment
03:50

Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment

Published on: August 2, 2024

2.0K
Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
06:41

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Published on: October 24, 2018

13.0K
A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

487

Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Sepsis Pathophysiology

Background:

  • Sepsis-associated acute kidney injury (AKI) affects a significant portion of patients, with mortality rates as high as 75% in severe cases.
  • Traditional management focused on improving renal blood flow, but recent evidence indicates renal blood flow is maintained or increased during septic shock.

Purpose of the Study:

  • To explore the multifactorial pathophysiology of sepsis-associated AKI (S-AKI).
  • To emphasize the importance of tailored treatment strategies, including renal replacement therapy (RRT), for S-AKI patients.

Main Methods:

  • Review of recent experimental studies and proposed theories on S-AKI.
  • Discussion of advancements in anticoagulation strategies and technologies for RRT in critically ill patients.

Main Results:

  • S-AKI is increasingly understood as a complex interplay of inflammation, oxidative stress, apoptosis, and microcirculatory dysfunction.
  • New anticoagulation strategies and technologies enable effective RRT, minimizing complications and downtime.

Conclusions:

  • Effective management of S-AKI requires a shift from solely hemodynamic support to addressing the integrated biological response to sepsis.
  • Enhanced collaboration between nephrologists and intensivists is crucial for implementing precision medicine approaches in critical care for S-AKI.