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Infections under Skin Flap After Cranioplasty and a Simple Effective Treatment

Jun-Hui Chen1, Wenwen Zhang, Zhong-Hua Shi

  • 1Anhui Medical University, Clinical Medical School, 904st Hospital of PLA (Wuxi Taihu Hospital), Department of Neurosurgery, Wuxi, China.

Turkish Neurosurgery
|April 16, 2019
PubMed
Abstract

Insights

A novel treatment combining antibiotics with continuous irrigation and drainage effectively cured titanium mesh cranioplasty infections, preserving the bone flap in all patients. This approach demonstrated no recurrence during long-term follow-up.

Area of Science:

  • Neurosurgery
  • Infectious Diseases
  • Biomaterials

Background:

  • Cranioplasty using titanium mesh is a common procedure.
  • Infection following titanium mesh cranioplasty presents a significant challenge.
  • Preserving the native bone flap in cases of infection is desirable.

Purpose of the Study:

  • To evaluate a new treatment protocol for titanium mesh cranioplasty infections.
  • To assess the efficacy and safety of this treatment in preserving the bone flap.
  • To report long-term outcomes of patients treated for infection.

Main Methods:

  • Retrospective review of 11 patients with post-cranioplasty infection.
  • Treatment involved sensitive antibiotics and enclosed continuous irrigation and drainage.
  • Follow-up ranged from 2 to 6 years to assess prognosis and security.

Main Results:

  • All 11 patients achieved complete cure and were discharged.
  • The infected bone flap (titanium mesh) was successfully preserved in all cases.
  • No recurrence of infection was observed during the 2- to 6-year follow-up period.

Conclusions:

  • A combination of sensitive antibiotics and enclosed continuous irrigation/drainage is effective for treating titanium mesh cranioplasty infections.
  • This treatment method is safe, easy, economical, and preserves the infected bone flap.
  • The described protocol offers a viable solution for managing post-cranioplasty infections.

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