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Related Concept Videos

Polymers02:34

Polymers

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The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
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G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.
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DNA Replication02:40

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DNA replication involves the separation of the two strands of the double helix, with each strand serving as a template from which the new complementary strand is copied.  After replication, each double-stranded DNA includes one parental or “old” strand and one “new” strand. This is known as semiconservative replication. The resulting DNA molecules have the same sequence and are divided equally into the two daughter cells.
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Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)01:20

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Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
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Vicinal or three-bond coupling is commonly observed between protons attached to adjacent carbons. Here, nuclear spin information is primarily transferred via electron spin interactions between adjacent C‑H bond orbitals. This generally favors the antiparallel arrangement of spins, so 3J values are usually positive.
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Dynamic Nanostructures from DNA-Coupled Molecules, Polymers, and Nanoparticles.

Shine K Albert1, Xiaole Hu1, So-Jung Park1

  • 1Department of Chemistry and Nanoscience, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul, 03760, Korea.

Small (Weinheim an Der Bergstrasse, Germany)
|April 16, 2019
PubMed
Summary

Researchers are developing dynamic DNA nanostructures that can change structure, properties, and motion in response to stimuli. These smart materials offer precise control for advanced applications.

Keywords:
DNADNA block copolymersdynamicnanoparticlesself-assemblystimuli-responsive

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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Molecular Engineering

Background:

  • Nature utilizes dynamic and reconfigurable systems for sensing and reacting to environmental signals.
  • Deoxyribonucleic acid (DNA) offers programmable molecular recognition, making it ideal for fabricating smart materials.
  • DNA-based self-assembly has enabled high-precision fabrication of DNA-organic and DNA-inorganic hybrid nanostructures.

Purpose of the Study:

  • To review recent advancements in dynamic DNA nanostructures.
  • To focus on hybrid structures incorporating DNA-conjugated molecules, polymers, and nanoparticles.
  • To discuss potential applications and future directions for these dynamic nanostructures.

Main Methods:

  • Exploration of DNA's programmable and responsive molecular recognition properties.
  • Utilizing DNA-based self-assembly for precise structural control in nanostructure fabrication.
  • Designing and assembling dynamic nanostructures capable of stimulus-responsive transformations.

Main Results:

  • Recent progress in creating dynamic nanostructures with on-demand structural, property, and motion changes.
  • Development of hybrid structures using DNA-conjugated molecules, polymers, and nanoparticles.
  • Demonstration of stimulus-responsive transformations in engineered DNA nanostructures.

Conclusions:

  • Dynamic DNA nanostructures represent a significant advancement in smart materials.
  • These hybrid nanostructures hold promise for diverse applications across science and technology.
  • Further research into dynamic DNA nanostructures will unlock new possibilities in responsive materials and devices.