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Updated: Jan 26, 2026

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Osteoporosis Circumscripta on 68Ga-DOTATATE PET CT
Nemi Gandy1, Katherine Louise Ordidge, Mubarik Arshad
1From the Nuclear Medicine Department, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road, London, United Kingdom.
Gallium-DOTATATE PET CT scans can reveal incidental findings like osteoporosis circumscripta. This case highlights the appearance of this Paget disease phase during carcinoid tumor staging.
Area of Science:
- Nuclear medicine
- Radiology
- Oncology
Background:
- Incidental findings are frequent in Positron Emission Tomography Computed Tomography (PET CT) scans.
- Gallium-68 (Ga)-DOTATATE distribution relies on somatostatin receptor expression, which can be pathological or physiological.
- Osteoporosis circumscripta, an early lytic phase of Paget disease, typically affects the skull and is identifiable on bone scans.
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