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Updated: Jan 26, 2026

Murine Model of Intestinal Ischemia-reperfusion Injury
Published on: May 11, 2016
Intestinal ischemia due to methamphetamine use: A case report
Kihoon Choi1, Andrew Imrie2, Rohan Lourie3
1Department of General Surgery, Mater Hospital Brisbane, Raymond Terrace, South Brisbane, Queensland, 4101, Australia.
Introduction:
Methamphetamine use is a rare cause of intestinal ischemia but is of clinical significance due to its high morbidity and mortality. Knowledge of methamphetamine-induced intestinal ischemia has been limited to few case reports.
Case Presentation:
We describe the case of a 48-year-old man who presented with ischemic bowel related to methamphetamine use. With concern for intestinal infarction the patient was taken to the operating room for emergency laparotomy, which found a segmental gangrene of small bowel and colon. The patient subsequently underwent right hemicolectomy and small bowel resection for damage control, followed by second-look laparotomy and anastomosis. The patient recovered well from the surgery and was discharged without complications.
Conclusion:
This case report alerts surgeons to have a high index of suspicion for intestinal ischemia in methamphetamine users who present with acute abdominal pain.
Insights
Methamphetamine use can cause rare but severe intestinal ischemia. Prompt surgical intervention is crucial for patient survival and recovery in these critical cases.
Area of Science:
- Gastroenterology
- Toxicology
- Surgical Case Reports
Background:
- Methamphetamine use is an uncommon but significant cause of intestinal ischemia.
- This condition is associated with high morbidity and mortality rates.
- Existing literature on methamphetamine-induced intestinal ischemia is sparse, primarily consisting of case reports.
Purpose of the Study:
- To report a case of ischemic bowel secondary to methamphetamine use.
- To highlight the clinical presentation and management of this rare condition.
- To increase awareness among surgeons regarding this potential complication.
Main Methods:
- A case presentation of a 48-year-old male patient with acute abdominal pain.
- Diagnostic workup including emergency laparotomy.
- Surgical intervention involving bowel resection and anastomosis.
Main Results:
- The patient presented with symptoms suggestive of ischemic bowel.
- Emergency laparotomy revealed segmental gangrene of the small bowel and colon.
- Successful surgical management with right hemicolectomy, small bowel resection, and subsequent anastomosis.
- The patient experienced an uncomplicated recovery and was discharged.
Conclusions:
- Methamphetamine use should be considered in the differential diagnosis of acute abdominal pain presenting with intestinal ischemia.
- A high index of suspicion is warranted in patients with a history of methamphetamine use.
- Early recognition and surgical management are vital for improving outcomes in methamphetamine-induced intestinal ischemia.
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