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Related Experiment Videos

Suppurative thrombophlebitis: correlation between pathogen and underlying disease.

R A Johnson, R A Zajac, M E Evans

    Infection Control : IC
    |December 1, 1986
    PubMed
    Summary

    Suppurative thrombophlebitis, a serious hospital-acquired infection, is linked to prolonged intravenous cannula use. Prompt surgical intervention is crucial for patient outcomes.

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    Area of Science:

    • Infectious Diseases
    • Surgical Pathology
    • Hospital Epidemiology

    Background:

    • Suppurative thrombophlebitis is a significant nosocomial infection.
    • Intravenous cannulae are frequently used in hospitalized patients.
    • Prolonged use of cannulae is a known risk factor for infection.

    Purpose of the Study:

    • To investigate the clinical characteristics and outcomes of suppurative thrombophlebitis.
    • To identify risk factors and associated pathogens.
    • To emphasize the importance of timely surgical intervention.

    Main Methods:

    • Retrospective review of 29 cases of suppurative thrombophlebitis.
    • Analysis of patient demographics, cannula dwell time, and implicated microorganisms.
    • Correlation of microbial findings with intra-abdominal pathology.

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    Main Results:

    • 27 patients experienced 29 episodes, with 25 involving cannulae in place >3 days.
    • Enteric organisms (e.g., Streptococcus faecalis, Pseudomonas aeruginosa) were associated with intra-abdominal pathology (14 patients).
    • Staphylococcus aureus and Candida species infections occurred in patients without active abdominal processes (13 patients).

    Conclusions:

    • Suppurative thrombophlebitis caused by enteric organisms shows a strong association with intra-abdominal pathology.
    • This condition is a lethal, preventable infection requiring urgent surgical management.
    • Delayed surgical intervention was linked to mortality.