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Updated: Jan 26, 2026

Tuning the Acidity of Pt/ CNTs Catalysts for Hydrodeoxygenation of Diphenyl Ether
Published on: August 17, 2019
Biosynthesis of Diphenyl Ethers in Fungi
Cheng Feng1, Qian Wei1, Changhua Hu1
1College of Pharmaceutical Sciences , Southwest University , Chongqing 400715 , P. R. China.
Abstract:
A new and concise biosynthetic pathway of fungal diphenyl ethers (DPEs) has been elucidated and efficiently reconstructed in yeast. The pathway includes an unusual nonreducing polyketide synthase (NRPKS) responsible for the formation of a polyketide dimer with an ether bond linkage as well as two cofactor-independent enzymes that catalyze tandem regioselective decarboxylation reactions. Our discovery here opens a new window for utilizing fungal DPEs as a platform to design and synthesize analogues for the development of highly useful drug leads.
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