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Dominant Lethal Assay of Spirulina maxima in Male CD-1 Mice after Short-Term and Prolonged-Term Feeding
1Laboratorio de Toxicología Preclínica, Depto. de Farmacia. Escuela Nacional de Ciencias Biológicas, IPN, Apartado Postal 105-314, Mexico D. F., Código Postal 11581, México.
Abstract:
Spirulina algae , incorporated into experimental diets at levels of 10, 20 or 30%, was given to groups of adult CD-1 mice. Short-term (5 d) and prolonged-term (5 d/week, for 10 weeks) feeding, was followed by mating with untreated adult virgin females. Examination of uteri and ovaries of pregnant females on d 12-14 of gestation for counting preimplantation losses and non-living implants failed to reveal dominant lethal effects.
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