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Ex vivo Expansion of Tumor-reactive T Cells by Means of Bryostatin 1/Ionomycin and the Common Gamma Chain Cytokines Formulation
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Secondary induction of cytotoxic T lymphocytes with solubilized syngeneic tumor cell plasma membranes

O Alaba, L W Law

    The Journal of Experimental Medicine
    |November 1, 1978
    PubMed

    Secondary induction of in vitro cytotoxic T lymphocytes in a syngeneic system has been achieved with plasma membrane, both in the particulate and solubilized forms. Both the induction and the lytic phases were shown to be immunologically specific. The effector cells generated were completely susceptible to treatment with anti-theta antibody and complement, suggesting that they are T lymphocytes.

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