Related Experiment Video
Updated: Jan 26, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Outcomes of Psychoeducation and a Text Messaging Adherence Intervention Among Individuals With Hypertension and
Jennifer B Levin1, Martha Sajatovic1, Mahboob Rahman1
1Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Objective:
This study evaluated the feasibility, acceptability, and preliminary efficacy of psychoeducation plus an automated text messaging intervention (Individualized Texting for Adherence Building-Cardiovascular [iTAB-CV]) to improve adherence to antihypertensives and bipolar disorder medication.
Methods:
After a psychoeducation program, iTAB-CV was administered for 2 months. In month 1, participants received one educational-motivational and one mood rating text daily. In month 2, medication reminders were added.
Results:
The sample (N=38) was 74% African American and 53% women, with a mean±SD age of 51.53±9.06. Antihypertensive nonadherence decreased from a mean of 43%±23% to 21%±18% at 12 weeks (χ2=34.6, df=3, p<0.001). Systolic blood pressure decreased from a mean of 144.8±15.5 mmHg to 136.0±17.8 mmHg (χ2=17.6, df=3, p<.001). Retention was 100%.
Conclusions:
In this uncontrolled trial, participants were highly engaged and medication adherence and reduced systolic blood pressure were sustained after psychoeducation plus iTAB-CV. Because iTAB-CV is automated and delivered remotely, it has the potential to reach a large and challenging population.
More Related Videos
05:48The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
Published on: June 12, 2020
06:16Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
Published on: June 6, 2020
Related Concept Videos
Bipolar Disorder
Nursing Interventions I: Taxonomy of Nursing Interventions
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...
Bipolar Junction Transistor
Nursing Interventions II: Selecting and Classifying the Nursing Interventions
Predicting Reaction Outcomes
Impact of Individuals on Individuals