Related Experiment Video
Updated: Jan 26, 2026

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
Published on: June 18, 2020
Countdown to 2030: eliminating hepatitis B disease, China
Jue Liu1, Wannian Liang2, Wenzhan Jing1
1Department of Epidemiology and Biostatistics, School of Public Health, Peking University, No.38, Xueyuan Road, Haidian District, Beijing 100191, China.
China has reduced hepatitis B virus (HBV) incidence through vaccination but needs to prioritize diagnosis and treatment to meet 2030 elimination goals. Key actions include enhancing medical capabilities and reducing patient costs.
Area of Science:
- Hepatology
- Public Health
- Infectious Diseases
Background:
- Hepatitis B virus (HBV) infection poses a significant global health challenge, with China bearing the largest burden.
- China has achieved substantial reductions in HBV incidence over three decades, primarily through high vaccination coverage.
- Despite progress, China faces challenges in meeting the 2030 target for a 65% reduction in hepatitis B mortality.
Purpose of the Study:
- To outline priorities for HBV elimination in China by 2030, aligning with the WHO Global Health Sector Strategy on Viral Hepatitis.
- To identify key areas for action to reduce hepatitis B mortality and achieve elimination targets.
Main Methods:
- Analysis of current HBV control strategies in China.
- Review of WHO targets for viral hepatitis elimination.
- Identification of gaps and recommendations for improving HBV diagnosis and treatment services.
Main Results:
- High vaccination coverage (>95%) has been successful in reducing HBV incidence.
- Significant gaps remain in the diagnosis and treatment of HBV infection.
- Existing national programs require better coordination for an integrated approach.
Conclusions:
- Prioritizing diagnosis and treatment services is crucial for reducing HBV mortality in China.
- Enhancing diagnostic and treatment capabilities of healthcare providers is essential.
- Reducing patient financial burdens and establishing integrated prevention and control systems are vital for HBV elimination by 2030.
Related Concept Videos
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Effect of Hepatic Disease on Pharmacokinetics: Active Drug, Metabolite and Fraction of Metabolized Drug
Kinetics of Drug Elimination
Drug clearance depends on the rate of drug elimination and its plasma concentration. Another important parameter is the half-life of a drug, which is the time required for its concentration to decrease by half. In most cases, drug clearance follows first-order...
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...

