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Updated: Jan 26, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade
Hong Yan1, Zhong-Yi Mao1, Zhong-Wei Hou1
1State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, iChEM and College of Chemistry and Chemical Engineering, Xiamen University, People's Republic of China.
Abstract:
A diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer.
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