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Living Donation by Individuals with Life-Limiting Conditions
Lainie Friedman Ross1, J Richard Thistlethwaite1
1Lainie Friedman Ross, M.D., Ph.D., is the Carolyn and Matthew Bucksbaum Professor of Clinical Ethics, Professor, Departments of Pediatrics, Medicine and Surgery, Associate Director, MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago IL. J. Richard Thistlethwaite, M.D., Ph.D., is Professor Emeritus, Department of Surgery and the MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago IL.
Insights
Living organ donation is expanding to include less healthy individuals. This paper explores the ethical considerations of donation by those with life-limiting conditions, including severe debilitating diseases or imminent death.
Area of Science:
- Transplantation ethics
- Medical ethics
- Organ donation policy
Background:
- Traditional living organ donors were typically very healthy.
- Increasing organ demand necessitates considering less healthy donors.
- This paper examines the extreme of living donation by individuals with life-limiting conditions.
Observation:
- Ethical dilemmas arise when considering donation from individuals with progressive, severe, debilitating diseases lacking curative treatments.
- Further ethical questions emerge regarding donation from individuals who are imminently dying or would die as a direct result of the donation process.
Findings:
- The paper identifies and discusses two primary ethical challenges in living organ donation.
- These challenges involve individuals with severe, untreatable progressive illnesses and those at the end of life.
Implications:
- This research informs ethical guidelines for organ transplantation programs.
- It prompts critical discussion on expanding the donor pool while prioritizing donor safety and ethical integrity.
- The findings contribute to policy development regarding organ donation from vulnerable populations.
Abstract:
The traditional living donor was very healthy. However, as the supply-demand gap continues to expand, transplant programs have become more accepting of less healthy donors. This paper focuses on the other extreme, asking whether and when individuals who have life-limiting conditions (LLC) should be considered for living organ donation. We discuss ethical issues raised by 1) donation by individuals with progressive severe debilitating disease for whom there is no ameliorative therapy; and 2) donation by individuals who are imminently dying or would die by the donation process itself.
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