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Clinical and laboratory profiles of children with severe chikungunya infection

Francisca Lillyan Christyan Nunes Beserra1, Gustavo Mesquita Oliveira1, Tino Miro Aurélio Marques1

  • 1Departamento de Saúde Comunitária, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.

Revista Da Sociedade Brasileira De Medicina Tropical
|April 18, 2019
PubMed

Insights

Chikungunya virus infection in children can manifest differently based on age. Severe cases in pediatric patients often involve systemic issues and unusual symptoms, requiring specific attention.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Clinical Medicine

Background:

  • Chikungunya virus infection exhibits age-specific clinical presentations.
  • Understanding these variations is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To describe the clinical features of chikungunya virus infection in hospitalized children.
  • To identify characteristics associated with severe disease in pediatric populations.

Main Methods:

  • Retrospective analysis of medical records.
  • Inclusion criteria: children with positive IgM for chikungunya virus.
  • Study setting: pediatric ward in Fortaleza, Ceará, Brazil.

Main Results:

  • Fourteen children (median age: 4 months) were analyzed.
  • All presented with fever (average 5 days).
  • Joint involvement occurred in 42.8%, and bullous rash in 57.1%.

Conclusions:

  • Severe chikungunya infection in children is characterized by systemic involvement.
  • Atypical clinical manifestations are indicative of severe disease in pediatric chikungunya cases.
Abstract

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