[Indications for determination of acrosin]

Assessment of acrosin activity for evaluation of acrosomal functions and the fertilizing capacity of spermatozoa is a suitable method within the diagnostic workup of male sterility in selected cases. Indications for determination of acrosin activity are cases with teratozoospermia and polyzoospermia. In addition, demonstration of sufficient amounts of acrosin activity in idiopathic sterility or in cases with an unknown male sterility factor and before in vitro fertilization may exclude severe disturbances of the sperm acrosome.