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Left ventricular geometry and risk of incident hypertension

Sung Keun Park1, Ju Young Jung2, Jeong Gyu Kang2

  • 1Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Heart (British Cardiac Society)
|April 19, 2019
PubMed

Insights

Left ventricular geometry changes predict cardiovascular disease. Echocardiographic measures like interventricular septal thickness (IVST) and posterior wall thickness (PWT) significantly increase hypertension risk in non-hypertensive individuals.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Hypertension Research

Background:

  • Left ventricular (LV) geometry is a known cardiovascular disease predictor.
  • The link between echocardiographic LV geometry and incident hypertension requires further clarification.

Purpose of the Study:

  • To investigate the association between baseline LV geometry parameters and the risk of developing hypertension.
  • To determine if echocardiographic measures predict incident hypertension in normotensive and prehypertensive individuals.

Main Methods:

  • 12,562 Koreans without hypertension underwent echocardiography.
  • Participants were categorized by baseline blood pressure (normotensive/prehypertensive) and LV geometry parameters (LVMI, RWT, IVST, PWT).
  • Cox proportional hazards and AUC analyses assessed hypertension risk and predictability over 5 years.

Main Results:

  • Prehypertensive individuals exhibited poorer baseline echocardiographic parameters.
  • Increased LVMI, RWT, IVST, PWT, and combined IVST+PWT were proportionally linked to higher hypertension risk.
  • IVST, PWT, and IVST+PWT demonstrated superior predictive ability for hypertension compared to LVMI.

Conclusions:

  • LV geometry changes are significantly associated with an elevated risk of hypertension.
  • Specific echocardiographic parameters of LV geometry can predict incident hypertension in individuals without diagnosed hypertension.
Abstract

Keywords:
echocardiographyhypertensionleft ventricular geometry

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