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Evaluation of referrals for short stature: A retrospective chart review
David Yue1,2,3, Michael R Miller3,4, Cheril L Clarson1,2,3
1Children's Hospital, London Health Sciences Centre, London, Ontario.
Insights
Height velocity (HV) is a key indicator for diagnosing pediatric endocrine disorders (PED) in children with short stature. Prompt access to previous measurements aids in calculating HV, leading to faster diagnosis and treatment.
Area of Science:
- Pediatric Endocrinology
- Growth Disorders
Background:
- Short stature referrals to pediatric endocrine clinics are frequent.
- Height velocity (HV) is crucial for evaluating short stature, as growth deceleration may indicate a pediatric endocrine diagnosis (PED).
- Previous growth measurements are essential for timely HV calculation.
Purpose of the Study:
- To assess the availability of prior growth measurements for short stature referrals.
- To identify predictors of a pediatric endocrine diagnosis (PED).
Main Methods:
- Retrospective chart review of short stature referrals (2008-2014).
- Standard protocol involved requesting previous measurements from referring physicians.
- Analysis of 286 patient charts (aged 11 months to 18 years).
Main Results:
- Previous measurements were available for 72.4% of patients.
- A pediatric endocrine diagnosis (PED) was identified in 44.8% of cases with available measurements.
- Height velocity below the 25th percentile and height deficit greater than 2 standard deviations significantly increased the odds of a PED.
Conclusions:
- Height velocity is a significant predictor of pediatric endocrine diagnoses.
- An effective referral screening protocol improved the availability of crucial growth data.
- Access to previous measurements facilitates HV calculation, potentially reducing diagnostic and management delays.
Background:
Referrals to paediatric endocrine clinics for short stature are common. Height velocity (HV) is an essential component of the evaluation of short stature as growth deceleration often reflects an underlying paediatric endocrine diagnosis (PED). Access to previous measurements facilitates prompt calculation of HV.
Objective:
To determine the availability of previous measurements at time of referral for short stature and to determine predictors of a PED.
Methods:
A retrospective chart review was performed on all referrals for short stature to a single paediatric endocrinologist between January 2008 and December 2014. Standard practice following receipt of a referral for short stature included repeated requests to the referring physician for previous measurements.
Results:
A total of 324 charts of patients aged 11 months to 18 years were reviewed and 286 were eligible for inclusion. Previous measurements were available in 72.4%, and 44.8% of these were found to have a PED. There was a significant relation between HV<25th percentile and a PED (P<0.0001) and between height deficit (HD) and a PED (P<0.0001). Logistic regression analysis showed that a HV<25th percentile and a HD>2 standard deviations, increased the odds of PED by a factor of 5.12 (P<0.001) and 1.39 (P<0.005), respectively.
Conclusion:
HV is a significant predictor of a PED. Our higher rate of previous measurement availability is likely due to our effective referral screening protocol. The availability of these measurements, which are essential for HV calculation, are likely to reduce delays in diagnosis and management.
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