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Determinants of inspiratory muscle function in healthy children

Theodore Dassios1,2, Gabriel Dimitriou2

  • 1Department of Child Health, King's College Hospital, Denmark Hill, London, SE5 9RS, UK.

Journal of Sport and Health Science
|April 19, 2019
PubMed

Insights

Inspiratory muscle function (TTImus) in children is influenced by gender, age, body size, and aerobic activity. This study establishes normal TTImus values for healthy children, highlighting key determinants.

Area of Science:

  • Pediatric Respiratory Medicine
  • Physiology
  • Exercise Science

Background:

  • Respiratory muscle disorders impact children's health.
  • Inspiratory muscle function is assessed using the noninvasive tension-time index of the inspiratory muscles (TTImus).
  • Understanding TTImus determinants in children is crucial for clinical assessment.

Purpose of the Study:

  • To identify factors influencing TTImus in healthy children.
  • To establish normative TTImus values for pediatric populations.
  • To analyze the relationship between anthropometry, aerobic activity, and TTImus.

Main Methods:

  • Measured weight, height, upper arm muscle area (UAMA), and TTImus in 96 children (aged 6-18).
  • Assessed aerobic activity levels via questionnaire.
  • Utilized multivariate logistic regression to identify independent predictors of TTImus.

Main Results:

  • TTImus was lower in males compared to females (p=0.002).
  • Regular exercisers showed lower TTImus than non-exercisers (p<0.001).
  • Height, age, weight, and UAMA were negatively correlated with TTImus; height and aerobic exercise were independent predictors.

Conclusions:

  • Gender, age, anthropometry, muscularity, and aerobic exercise are significantly associated with pediatric inspiratory muscle function.
  • Normal TTImus values for healthy children are reported.
  • Height and aerobic exercise independently predict TTImus in children.
Abstract

Keywords:
Aerobic exerciseChildrenInspiratory muscle functionMaximal inspiratory pressureSkeletal muscle functionTension–time index of the inspiratory muscles

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