Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanism of Breathing I: Inspiration01:30

Mechanism of Breathing I: Inspiration

3.1K
Introduction to Inspiration: The Respiratory System in Action
The respiratory system, an essential network for breathing, comprises the conducting and respiratory zones, each playing a crucial role in the overall process of respiration. Let us explore the detailed mechanism of inspiration, or inhalation, which is the first phase of the respiratory cycle.
Pathway of Air during Inspiration
During inspiration, air enters our body through the nose or mouth and moves through the conducting zone,...
3.1K
Oxidation Numbers03:14

Oxidation Numbers

42.3K
In redox reactions, the transfer of electrons occurs between reacting species. Electron transfer is described by a hypothetical number called the oxidation number (or oxidation state). It represents the effective charge of an atom or element, which is assigned using a set of rules.
42.3K
Pyruvate Oxidation01:15

Pyruvate Oxidation

168.5K
After glycolysis, the charged pyruvate molecules enter the mitochondria via active transport and undergo three enzymatic reactions. These reactions ensure that pyruvate can enter the next metabolic pathway so that energy stored in the pyruvate molecules can be harnessed by the cells.
First, the enzyme pyruvate dehydrogenase removes the carboxyl group from pyruvate and releases it as carbon dioxide. The stripped molecule is then oxidized and releases electrons, which are then picked up by NAD+...
168.5K
Oxidation-Reduction Reactions03:11

Oxidation-Reduction Reactions

75.3K
Oxidation–Reduction Reactions
75.3K
Oxidation of Alcohols02:37

Oxidation of Alcohols

15.8K
In this lesson, the oxidation of alcohols is discussed in depth. The various reagents used for oxidation of primary and secondary alcohols are detailed, and their mechanism of action is provided.
The process of oxidation in a chemical reaction is observed in any of the three forms:
15.8K
Modified Boxplots00:57

Modified Boxplots

10.8K
A standard box and whisker plot informs us about the spread of the data in a given sample. One can identify the minimum value, maximum value, first quartile value, second quartile or median value, and third quartile.
However, the box plot does not tell the reader about outliers - values that lie far from the center of the data. We can modify the standard box and whisker plot to identify the outliers and visualize the actual spread of the data in a sample.
Initially, we calculate the adjusted...
10.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synergistic effect of carbon fabric metastructure and magnetic layers in a composite for electromagnetic radiation shielding.

Scientific reports·2026
Same author

Amphiphilic Hollow Microgels at the Liquid-Liquid Interface: Studying Soft Colloids' Shape and Interior via Computer Simulations and Machine Learning.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Tailored Nanogel Network Topology Enables Clinical Ultrasound-Induced Mechanochemical Activation for In Vivo Therapy.

Angewandte Chemie (International ed. in English)·2026
Same author

Oxygen-Inhibition Driven Compartmentalization of Dextran Microgels: Toward Fusible Colloidal Biomaterial Inks for 3D Printing.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Green Synthesis of Biobased NIPUrea-Acrylate Hybrids for Versatile, Fast-Curing Hot-Melt Coating Development.

ACS applied materials & interfaces·2025
Same author

Microbubble Shell Stiffness Engineering Enhances Ultrasound Imaging, Drug Delivery, and Sonoporation.

Advanced materials (Deerfield Beach, Fla.)·2025

Related Experiment Video

Updated: Jan 26, 2026

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
07:58

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles

Published on: November 14, 2018

8.7K

Selenium-Modified Microgels as Bio-Inspired Oxidation Catalysts.

Kok H Tan1, Wenjing Xu1, Simon Stefka1

  • 1DWI Leibniz Institute for Interactive Materials e.V., RWTH Aachen University, Forckenbeckstraße 50, 52074, Aachen, Germany.

Angewandte Chemie (International Ed. in English)
|April 19, 2019
PubMed
Summary

Researchers developed active colloidal catalysts by incorporating selenium into microgels, mimicking glutathione peroxidase (GPx). These novel selenium-based microgels show enhanced catalytic activity for oxidation reactions at low temperatures.

Keywords:
microgelsorganocatalysisredox chemistryselenium

More Related Videos

Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area
08:13

Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area

Published on: February 19, 2018

12.4K
Author Spotlight: Development of Homogeneous κ-Carrageenan Sub-Microgel Baths for High-Resolution 3D Bioprinting
04:58

Author Spotlight: Development of Homogeneous κ-Carrageenan Sub-Microgel Baths for High-Resolution 3D Bioprinting

Published on: May 3, 2024

1.8K

Related Experiment Videos

Last Updated: Jan 26, 2026

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
07:58

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles

Published on: November 14, 2018

8.7K
Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area
08:13

Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area

Published on: February 19, 2018

12.4K
Author Spotlight: Development of Homogeneous κ-Carrageenan Sub-Microgel Baths for High-Resolution 3D Bioprinting
04:58

Author Spotlight: Development of Homogeneous κ-Carrageenan Sub-Microgel Baths for High-Resolution 3D Bioprinting

Published on: May 3, 2024

1.8K

Area of Science:

  • Materials Science
  • Catalysis
  • Polymer Chemistry

Background:

  • Glutathione peroxidase (GPx) enzymes are crucial for antioxidant defense, utilizing selenium for their catalytic activity.
  • Developing synthetic catalysts that mimic GPx activity is essential for various chemical applications.
  • Selenium-containing materials offer unique catalytic properties but often face challenges in stability and controlled synthesis.

Purpose of the Study:

  • To synthesize active colloidal catalysts by integrating selenium moieties into aqueous microgels.
  • To investigate the catalytic activity and selectivity of these novel microgels in oxidation reactions.
  • To compare the performance of the microgel catalysts with molecular selenium catalysts.

Main Methods:

  • Synthesis of a diselenide crosslinker (Se X-linker).
  • Incorporation of the Se X-linker into aqueous microgels via precipitation polymerization alongside N,N'-methylenebis(acrylamide) (BIS).
  • Oxidative cleavage of diselenide bonds to form catalytically active seleninic acid within the microgel structure.
  • Evaluation of catalytic performance in a model oxidation reaction (acrolein to acrylic acid and methyl acrylate).

Main Results:

  • Successfully synthesized microgels containing catalytically active selenium moieties.
  • Demonstrated that diselenide bonds could be converted to seleninic acid while preserving microgel integrity.
  • Achieved variable amounts of seleninic acid within the microgel structure.
  • Observed higher catalytic activity and selectivity at low temperatures compared to molecular selenium catalysts.

Conclusions:

  • Active colloidal catalysts inspired by GPx were successfully synthesized using selenium-integrated microgels.
  • The microgel-based selenium catalysts exhibit superior performance in terms of activity and selectivity under mild conditions.
  • This approach offers a promising strategy for developing robust and efficient selenium-based catalysts for oxidation reactions.