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Plasma proteomics and the paediatric patient

Conor McCafferty1, Jessica Chaaban1, Vera Ignjatovic1,2

  • 1a Haematology Research Laboratory, Murdoch Children's Research Institute , Melbourne , Australia.

Expert Review of Proteomics
|April 19, 2019
PubMed

Insights

Pediatric plasma proteomics is expanding, offering new avenues for early disease detection and prevention in children. This field is crucial for long-term health outcomes, marking a new era in medical science.

Area of Science:

  • Biomedical science
  • Proteomics
  • Pediatric research

Background:

  • Plasma proteomics is widely used in adult disease and drug studies.
  • Pediatric plasma proteomic research is currently limited.
  • Early disease detection is vital in pediatrics due to long-term health implications.

Purpose of the Study:

  • To comprehensively review plasma proteomic studies in pediatric patients.
  • To highlight the significance of pediatric plasma proteomics.
  • To discuss the expansion of this research area.

Main Methods:

  • Literature review based on a PubMed search.
  • Keywords: plasma, biomarkers, pediatric, proteomics, children.
  • Analysis of clinical settings, sample sizes, and methodologies.

Main Results:

  • Pediatric plasma proteomics is an underrepresented but expanding field.
  • Advancements in proteomic technology are driving this growth.
  • The review synthesizes findings from existing pediatric studies.

Conclusions:

  • Pediatric plasma proteomics is poised for significant expansion.
  • This field is synergistic with the focus on early disease detection and prevention.
  • A new era of advanced medical science in pediatrics is emerging.
Abstract

Keywords:
Biomarkerschildrenpediatricplasmaproteomics

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