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MRI-guided frame-based stereotactic brainstem biopsy procedure: A single-center experience.
1Department of Neurosurgery, Kent Hospital, İzmir, Turkey.
Neurocirugia (English Edition)
|April 20, 2019
Summary
MRI-guided stereotactic brainstem biopsy is a safe and effective method for diagnosing brainstem lesions. This procedure demonstrated high diagnostic accuracy with no major complications in 18 patients.
Area of Science:
- Neurosurgery
- Neurology
- Radiology
Background:
- Brainstem lesions require accurate histopathological diagnosis for effective treatment.
- Stereotactic biopsy offers a minimally invasive approach to access deep brain lesions.
Purpose of the Study:
- To present experience and evaluate outcomes of MRI-guided frame-based stereotactic brainstem biopsy.
- To assess the safety, efficacy, and diagnostic yield of this technique.
Main Methods:
- Retrospective analysis of 18 patients undergoing MRI-guided frame-based stereotactic brainstem biopsy (2011-2018).
- Data collected on biopsy technique, morbidity, histopathological diagnosis, and diagnostic accuracy.
- Procedures guided by MRI, with local anesthesia for adults and local anesthesia with sedation for children.
Main Results:
- Successful histopathological diagnosis was achieved in all 18 patients.
- No equivocal or negative results were reported.
- No major morbidity or mortality occurred post-procedure.
Conclusions:
- MRI-guided frame-based stereotactic biopsy is a safe and efficient diagnostic tool for brainstem lesions.
- Optimizing trajectory selection, MRI guidance, and sample size are key to minimizing morbidity.
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