[Continuation of ICD treatment at the time of device exchange without adequate treatment?]

Konstantin Krieger1, Corinna Lenz2

  • 1Klinik für Innere Medizin und Kardiologie, Unfallkrankenhaus Berlin, Warenerstraße 7, 12683, Berlin, Deutschland. Konstantin.Krieger@ukb.de.

Insights

Elective implantable cardioverter-defibrillator (ICD) replacement offers a chance to reassess treatment for patients with heart failure. Discontinuing ICD therapy may be an option for select patients, considering factors like ejection fraction and comorbidities.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Device Technology

Background:

  • Increasingly older heart failure patients with comorbidities undergo elective device exchange.
  • This demographic shift necessitates re-evaluating implantable cardioverter-defibrillator (ICD) treatment protocols.
  • Higher complication rates in this population highlight the need for individualized care.

Purpose of the Study:

  • To review literature on continuing ICD therapy versus device exchange in patients without adequate ICD treatment.
  • To explore criteria for discontinuing or modifying ICD therapy during elective replacement.

Main Methods:

  • Literature review focusing on patients with prophylactic ICD indications and no adequate treatment.
  • Analysis of factors influencing ventricular arrhythmia (VA) risk, including left ventricular ejection fraction (LVEF).
  • Consideration of patient demographics (age, sex) and comorbidities.

Main Results:

  • Patients with improved LVEF (>35%) and prophylactic ICD indications have a lower VA risk post-exchange.
  • Individualized discussion is crucial for continuing ICD treatment in older patients with comorbidities.
  • Discontinuation or downgrading to CRT-P may be suitable for female patients with non-ischemic cardiomyopathy and normalized LVEF, especially with CRT.

Conclusions:

  • Discontinuation of ICD therapy can be considered during elective exchange for prophylactic indications in untreated patients.
  • Individualized decisions require assessment of LVEF, age, sex, and comorbidities.
  • Lack of prospective randomized studies prevents general recommendations.
Abstract

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