Outcomes of Zygomatic Complex Reconstruction With Patient-Specific Titanium Mesh Using Computer-Assisted Techniques

Area of Science:

• Oral and Maxillofacial Surgery
• Reconstructive Surgery
• Biomaterials Engineering

Background:

• Extensive maxillectomy can lead to significant zygomatic complex defects, impacting facial aesthetics and function.
• Patient-specific implants offer a promising solution for complex midface reconstruction.

Purpose of the Study:

• To evaluate the clinical application and outcomes of patient-specific titanium mesh for zygomatic complex reconstruction after maxillectomy.

Main Methods:

• Retrospective study of 9 patients undergoing zygomatic complex reconstruction with patient-specific titanium mesh.
• 3D modeling based on contralateral side for mesh fabrication.
• Free flap reconstruction (anterolateral thigh or fibula flap) used in conjunction with mesh.
• Postoperative CT scans and patient self-evaluation assessed symmetry and complications.

Main Results:

• Mean follow-up of 27.3 months.
• Excellent symmetry achieved with mean deviation of 1.4 mm between reconstructed and unaffected sides (P=0.591).
• One case of titanium mesh exposure post-radiotherapy; no other major complications reported. High patient satisfaction with aesthetic outcomes.

Conclusions:

• Patient-specific titanium mesh is a viable option for extensive zygomatic complex reconstruction, yielding satisfactory clinical results.
• Further research with larger cohorts and extended follow-up is recommended to assess long-term efficacy and complication risks.