Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Common Ion Effect03:24

Common Ion Effect

46.2K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:
46.2K
Internal Receptors01:31

Internal Receptors

74.4K
Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
74.4K
Common Respiratory Disorders01:31

Common Respiratory Disorders

1.3K
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.3K
Receptor-mediated Endocytosis01:39

Receptor-mediated Endocytosis

110.7K
Overview
110.7K
Enzyme-linked Receptors01:00

Enzyme-linked Receptors

86.4K
Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
86.4K
G-protein Coupled Receptors01:21

G-protein Coupled Receptors

131.7K
G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.
131.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aqueous-based lignin extractions from birch, wheat, and oat exhibit broad antimicrobial activities.

International journal of biological macromolecules·2025
Same author

Selected strains of the Ganoderma lucidum complex from Finnish forests have excellent broadly acting antiviral properties.

Scientific reports·2025
Same author

Immunological and structural evaluation of the intranasally administrated CVB1 whole-virus and VLP vaccines.

Scientific reports·2025
Same author

Vemurafenib inhibits the replication of diabetogenic enteroviruses in intestinal epithelial and pancreatic beta cells.

Antiviral research·2024
Same author

A rosin-functionalized plastic surface inactivates African swine fever virus.

Frontiers in veterinary science·2024
Same author

Impact of HDAC inhibitors on macrophage polarization to enhance innate immunity against infections.

Drug discovery today·2024

Related Experiment Video

Updated: Jan 26, 2026

Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors
12:03

Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors

Published on: June 7, 2016

18.4K

A Common Receptor Found for Echoviruses.

Mira Laajala1, Varpu Marjomäki1

  • 1Department of Biological and Environmental Science, Nanoscience Center, University of Jyväskylä, PO, Box 35, FI-40014 Jyväskylä, Finland.

Trends in Microbiology
|April 21, 2019
PubMed
Summary

Neonatal Fc receptor acts as a pan receptor for echoviruses, explaining infant susceptibility to enterovirus infections. This discovery sheds light on early-life viral vulnerability.

Keywords:
Echovirus infectionsFc receptorenterovirusesneonates

More Related Videos

A BW Reporter System for Studying Receptor-Ligand Interactions
06:05

A BW Reporter System for Studying Receptor-Ligand Interactions

Published on: January 7, 2019

8.1K
Author Spotlight: Optimizing Micro-Drive Systems for Precise Electrode Positioning in Marmoset
07:37

Author Spotlight: Optimizing Micro-Drive Systems for Precise Electrode Positioning in Marmoset

Published on: August 4, 2023

1.4K

Related Experiment Videos

Last Updated: Jan 26, 2026

Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors
12:03

Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors

Published on: June 7, 2016

18.4K
A BW Reporter System for Studying Receptor-Ligand Interactions
06:05

A BW Reporter System for Studying Receptor-Ligand Interactions

Published on: January 7, 2019

8.1K
Author Spotlight: Optimizing Micro-Drive Systems for Precise Electrode Positioning in Marmoset
07:37

Author Spotlight: Optimizing Micro-Drive Systems for Precise Electrode Positioning in Marmoset

Published on: August 4, 2023

1.4K

Area of Science:

  • Virology
  • Immunology
  • Neonatal Medicine

Background:

  • Infants are highly susceptible to enterovirus infections in early life.
  • The precise mechanisms underlying this vulnerability remain incompletely understood.

Purpose of the Study:

  • To investigate the role of the neonatal Fc receptor in echovirus infections.
  • To elucidate the cellular mechanisms contributing to infant susceptibility to enteroviruses.

Main Methods:

  • Utilized the neonatal Fc receptor as a pan-receptor model.
  • Investigated echovirus interactions with neonatal Fc receptor in various tissues.

Main Results:

  • Demonstrated that the neonatal Fc receptor functions as a pan-receptor for multiple echovirus serotypes.
  • Identified the neonatal Fc receptor as a key factor in facilitating echovirus entry and infection in neonates.

Conclusions:

  • The neonatal Fc receptor plays a critical role in mediating echovirus infections in infants.
  • Understanding this interaction provides insight into early-life viral pathogenesis and potential therapeutic targets.