Related Experiment Video
Updated: Jan 26, 2026
06:56
Somatosensory Event-related Potentials from Orofacial Skin Stretch Stimulation
Published on: December 18, 2015
13.8K
Transepidermal Potential of the Stretched Skin
Yuina Abe1, Hajime Konno2, Shotaro Yoshida3
1Department of Finemechanics,Graduate School of Engineering,Tohoku University,6-6-01 Aramaki Aoba,Sendai 980-8579, Japane-mail: abe@biomems.mech.tohoku.ac.jp.
Journal of Biomechanical Engineering
|April 21, 2019
Summary
Skin
Area of Science:
- Biophysics
- Materials Science
Background:
- The skin's electrical properties are crucial for its barrier function.
- Understanding the electro-mechanical coupling in skin is vital for developing advanced biomaterials and medical devices.
Purpose of the Study:
- To investigate the real-time electrical response of porcine skin to mechanical stretching.
- To characterize the transepidermal potential (TEP) changes under cyclic strain.
- To determine the specific skin layer responsible for the observed electrical changes.
Main Methods:
- Measurement of transepidermal potential (TEP) using conventional and a novel probe-type system.
- Application of cyclic mechanical stretches to porcine skin samples.
- Comparative analysis of TEP changes in epidermis, dermis, and hypodermis.
Main Results:
- TEP significantly decreased with increasing mechanical stretch.
- Electrical changes were localized primarily within the epidermis.
- TEP modulation was rapid, reversible, and strain-dependent.
Conclusions:
- Mechanical stretching alters the electrical properties of the epidermis.
- Streaming potential due to fluid flow during deformation is a likely mechanism for TEP modulation.
- Findings provide insights into the electro-mechanical behavior of skin for potential applications.
Related Concept Videos
01:24IR Frequency Region: X–H Stretching
1.4K
In IR spectroscopy, signals produced by the X−H bonds (such as C−H, O−H, or N−H) can be observed in the frequency range of 2700–4000 cm–1. The C−H stretching vibration forms sharp bands in the region 2850–3000 cm–1. The presence of the O−H stretching vibration leads to the forming of an absorption band in the frequency range 3650–3200 cm−1. At the same time, N−H stretching can be confirmed by absorption bands in...
1.4K
01:22IR Frequency Region: Alkyne and Nitrile Stretching
1.4K
Both alkyne (C≡C) and nitrile (C≡N) functional groups contain triple bonds and show stretching absorptions around the wavenumber range of 2100 to 2300 cm−1 in the diagnostic region of the IR spectra.
Comparing the stretching vibrational frequency of C≡C triple bonds with that of double and single bonds, it is evident that C≡C triple bonds exhibit a higher stretching frequency than C=C double and C–C single bonds. Similarly, the C≡N triple bond...
Comparing the stretching vibrational frequency of C≡C triple bonds with that of double and single bonds, it is evident that C≡C triple bonds exhibit a higher stretching frequency than C=C double and C–C single bonds. Similarly, the C≡N triple bond...
1.4K
01:29IR Frequency Region: Alkene and Carbonyl Stretching
1.3K
Double bonds in alkenes and carbonyl compounds exhibit stretching frequencies in the diagnostic region of the IR spectrum. In addition, alkenes exhibit vinylic C–H stretching and C–H out-of-plane bending absorptions that are useful for identifying substitution patterns.
Stretching frequencies are affected by several factors, such as resonance, inductive effects, ring strain, dipole moment, and hydrogen bonding. Consequently, the stretching frequency of the carbonyl double bond...
Stretching frequencies are affected by several factors, such as resonance, inductive effects, ring strain, dipole moment, and hydrogen bonding. Consequently, the stretching frequency of the carbonyl double bond...
1.3K
00:52Potential Energy
42.4K
The energy stored by a structure and location of matter in space is called potential energy. For instance, raising a kettlebell changes its spatial location and increases its potential energy. Similarly, a stretched rubber band contains potential energy which, under certain conditions, can be converted into other forms of energy, such as kinetic energy.
Chemical bonds that form attractive forces between atoms also contain potential energy, called chemical energy. When a chemical reaction...
Chemical bonds that form attractive forces between atoms also contain potential energy, called chemical energy. When a chemical reaction...
42.4K
01:09Potential Energy
984
A conservative force, such as a gravitational or elastic force, gives the body the capacity to do work. This capacity, measured as the potential energy, depends on the body's location or “position” relative to a fixed reference position or datum. The gravitational potential energy is considered zero at the reference point. Suppose a body is located at some vertical distance above a fixed horizontal reference or datum. In that case, the weight of the body has positive gravitational potential...
984
03:02Standard Electrode Potentials
50.0K
On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
50.0K