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Updated: Jan 26, 2026

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Viral Tracing of Genetically Defined Neural Circuitry
Published on: October 17, 2012
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Trans-synaptic Neural Circuit-Tracing with Neurotropic Viruses
Jiamin Li1,2, Taian Liu1, Yun Dong1
1Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, The Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Neuroscience Bulletin
|April 21, 2019
Summary
Neurotropic viruses are powerful tools for mapping brain connections. This review highlights recent advancements in viral neuronal tracers for understanding neural circuits in health and disease.
Area of Science:
- Neuroscience
- Molecular Biology
- Virology
Background:
- Understanding neural circuits is crucial for deciphering nervous system function and disease.
- Neurotropic viruses exhibit a natural ability to spread between synaptically connected neurons.
Purpose of the Study:
- To review recent developments in neurotropic viral tracers.
- To highlight the unique properties of these viral tools for neural circuit mapping.
Main Methods:
- Review of current literature on viral neuronal tracers.
- Analysis of viral properties relevant to neural circuit delineation.
Main Results:
- Several classes of viral neuronal tracers are now available.
- These tracers offer a powerful toolbox for mapping neural networks.
Conclusions:
- Neurotropic viral tracers are essential for understanding neural connectivity.
- Recent advancements enhance their utility in neuroscience research.
Keywords:
Anterograde tracingCentral nervous systemNeural circuitNeurotropic virusRetrograde tracingTrans-synaptic tracerMore Related Videos
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