Related Experiment Video
Updated: Jan 26, 2026

05:39
Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
2.2K
Is there a correlation between thyroiditis and thyroid cancer?
Paolo Del Rio1, Chiara Montana Montana2, Federico Cozzani2
1General Surgery Unit, University Hospital of Parma, Parma, Italy. paolo.delrio@unipr.it.
Endocrine
|April 21, 2019
Summary
This study investigated the link between thyroiditis and thyroid cancer, finding no statistically significant correlation. While thyroiditis was slightly more common in thyroid cancer cases, further research is needed to define any potential relationship.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- Global incidence of thyroid cancer and Hashimoto's thyroiditis has risen in recent decades.
- Existing research suggests a potential link between thyroiditis and thyroid cancer.
Purpose of the Study:
- To evaluate the association between thyroiditis and the incidence of thyroid cancer.
- To determine if thyroiditis is a risk factor for developing thyroid cancer.
Main Methods:
- Analysis of 2304 thyroid surgery cases over 12 years.
- Histological diagnosis of thyroiditis in benign (Group A) and malignant (Group B) thyroid classifications.
- Comparison of thyroiditis prevalence between benign and malignant groups.
Main Results:
- Thyroiditis was observed in 36.4% of malignant cases (Group B) and 32.4% of benign cases (Group A).
- No statistically significant difference in thyroiditis incidence was found between the two groups (P > 0.05).
Conclusions:
- The current study could not establish a definitive correlation between thyroiditis and an increased incidence of thyroid cancer.
- Further investigation is required to clarify the relationship between these conditions.
Related Concept Videos
The Thyroid Gland
6.9K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
6.9K
Functions of Thyroid Hormones
5.1K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
5.1K
Synthesis and Regulation of Thyroid Hormones
7.4K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
7.4K
Correlations
35.8K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
35.8K
Correlation and Causation
42.4K
Statistical tests can calculate whether there is a relationship, or correlation, between independent and dependent variables. An indirect relationship of the variables signifies a correlation, while a direct relationship shows causation. If it is determined that no connection exists between the variables, then the correlation is a coincidence.
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...
42.4K
Correlation
14.8K
In statistics, two variables are said to be correlated if the values of one variable are associated with the other variable. Depending on the relationship between two variables, correlation can be of three types– positive correlation, negative correlation, and zero correlation.
Two variables, for example, a and b, are said to be positively correlated if both variables move in the same direction. In other words, a positive correlation exists between two variables, a and b, if:
Two variables, for example, a and b, are said to be positively correlated if both variables move in the same direction. In other words, a positive correlation exists between two variables, a and b, if:
14.8K

