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Femoral Artery Sclerosis Evaluation by Tissue Doppler in Patients with Hypertension

Xianghong Lei1, Juan Liu1

  • 1Department of Ultrasonography, Tianjin Union Medical Center (Tianjin People's Hospital), Tianjin, China (mainland).

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
|April 21, 2019
PubMed

Insights

Tissue Doppler imaging (TDI) effectively detects early femoral artery sclerosis in hypertensive patients. This method identifies arterial changes before intima-media thickness (IMT) alterations become apparent, aiding in early diagnosis.

Area of Science:

  • Cardiovascular Imaging
  • Vascular Ultrasound
  • Hypertension Research

Background:

  • Hypertension is a significant risk factor for cardiovascular disease.
  • Early detection of vascular changes in hypertensive patients is crucial for intervention.
  • Femoral artery intima-media thickness (IMT) is a marker of atherosclerosis.

Purpose of the Study:

  • To evaluate the efficacy of tissue Doppler imaging (TDI) in detecting early femoral artery sclerosis in hypertensive patients.
  • To compare TDI parameters with femoral artery IMT measurements.
  • To assess TDI's potential as an early diagnostic tool for femoral artery disease.

Main Methods:

  • One hundred hypertensive patients were divided into two groups based on femoral artery IMT (≥1.0 mm and <1.0 mm).
  • Fifty healthy individuals served as controls.
  • High-frequency ultrasound and pulsed wave TDI were used to examine femoral artery wall structure, IMT, and posterior wall motion, obtaining first (T1) and second (T2) peak durations.

Main Results:

  • Significant differences in femoral artery IMT were observed between the groups (P<0.05).
  • No significant difference in T1 peak duration was found across the groups (P=0.158).
  • A statistically significant difference in T2 peak duration was noted between hypertensive patients and controls (F=50.411, P=0.000), with higher values in hypertensive groups.

Conclusions:

  • TDI, specifically the second peak duration (T2), serves as an effective index for identifying early femoral artery sclerosis.
  • TDI can detect arterial changes prior to significant alterations in femoral artery IMT.
  • TDI shows promise as a valuable tool for the early diagnosis of atherosclerosis in hypertensive individuals.

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