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Updated: Jan 26, 2026
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In situ TEM of Biological Assemblies in Liquid
Published on: December 30, 2013
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Integration of biological systems with electronic-mechanical assemblies.
Ning Yi1, Haitao Cui2, Lijie Grace Zhang3
1Department of Materials Science and Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
Acta Biomaterialia
|April 21, 2019
Summary
Bio-integrated devices merge biological systems with electronic-mechanical assemblies for enhanced monitoring and therapeutic interventions. This integration offers a fundamental understanding of biological system interactions across various scales.
Area of Science:
- Bio-integrated electronics
- Biomedical engineering
- Materials science
Background:
- Biological systems dynamically interact with their environment through diverse cues.
- Understanding these interactions is crucial for advancing healthcare and biological research.
- Recent innovations enable sophisticated interfaces between biological and electronic systems.
Purpose of the Study:
- To review recent advancements in integrating biological systems with electronic-mechanical assemblies.
- To highlight the opportunities for simultaneous monitoring and eliciting biological responses.
- To provide a fundamental understanding of bio-electronic-mechanical interactions.
Main Methods:
- Review of recent literature on bio-integrated device development.
- Focus on innovations in materials, fabrication, and device integration.
- Exploration of applications across multiple biological scales.
Main Results:
- Successful integration of biological systems with electronic-mechanical assemblies.
- Development of bio-integrated devices capable of interfacing from cellular to individual levels.
- Emergence of applications in healthcare monitoring, drug delivery, and rehabilitation.
Conclusions:
- Bio-integrated devices offer unprecedented opportunities for studying biological systems.
- Innovations in materials and fabrication are key enablers for these advanced interfaces.
- The field holds significant promise for future healthcare and therapeutic applications.
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