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Related Experiment Videos

Diagnostic pathways in Crohn's disease.

N Rao1, S Kumar2, S Taylor2

  • 1Department of Radiology, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, UK.

Clinical Radiology
|April 22, 2019
PubMed
Summary
This summary is machine-generated.

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Crohn's disease (CD) management is shifting towards early combined immunosuppression. Advanced imaging is crucial for accurate assessment, guiding treatment goals, and improving patient outcomes in CD.

Area of Science:

  • Gastroenterology
  • Radiology
  • Immunology

Background:

  • Crohn's disease (CD) management is evolving from symptom-based care to early aggressive immunosuppression to prevent bowel damage.
  • Accurate assessment of CD activity is challenging due to discrepancies between symptoms and disease status.
  • Imaging plays a pivotal role in CD diagnosis, phenotype characterization, activity assessment, surveillance, and treatment response evaluation.

Purpose of the Study:

  • To review current imaging techniques for Crohn's disease (CD).
  • To guide radiologists on preferred imaging options for CD diagnosis and management.
  • To discuss the role of imaging in the "treat-to-target" approach for CD.

Main Methods:

  • Review of principal imaging techniques used in CD diagnosis and management.

Related Experiment Videos

  • Analysis of key imaging findings and their interpretation.
  • Discussion of the merits and drawbacks of various imaging modalities.

    • Main Results:

    • Imaging is central to establishing CD diagnosis, characterizing phenotype, assessing activity, and monitoring treatment.
    • Cross-sectional imaging demonstrating resolution of transmural inflammation is a key target in CD management.
    • Imaging facilitates a "treat-to-target" strategy by providing objective measures of disease activity.

    Conclusions:

    • The role of imaging in Crohn's disease (CD) has expanded significantly, becoming integral to modern management strategies.
    • Optimizing imaging service configuration and delivery is essential for accurate and cost-effective CD care.
    • Future research directions in CD imaging are crucial for advancing treatment and patient outcomes.