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Preparation of Binary and Ternary Deep Eutectic Systems
Published on: October 31, 2019
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Ionic deep eutectic solvents for the extraction and separation of natural products
Jie Huang1, Xiuyun Guo1, Tianyi Xu1
1Research Center of Siyuan Natural Pharmacy and Biotoxicology, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang Province 310058, China.
Journal of Chromatography. A
|April 22, 2019
Summary
Deep eutectic solvents (DESs) offer a sustainable, cost-effective alternative to ionic liquids (ILs) for extracting natural products. This review focuses on ionic DES preparation and application, highlighting factors influencing extraction efficiency.
Area of Science:
- Green chemistry and sustainable solvent technologies.
- Exploration of novel solvent systems for natural product isolation.
Background:
- Ionic liquids (ILs) are established green solvents with wide applications.
- Deep eutectic solvents (DESs) emerge as promising alternatives due to lower cost and easier preparation.
- DESs share desirable properties with ILs, including stability and low vapor pressure.
Purpose of the Study:
- To provide an overview of deep eutectic solvents (DESs), with a focus on ionic DESs.
- To discuss the preparation and application of choline-based DESs in natural product extraction.
- To examine factors affecting the efficiency of DES-mediated extraction and recovery.
Main Methods:
- Review of literature on DES preparation and characterization.
- Analysis of DES applications in natural product extraction, particularly from traditional Chinese medicines.
- Discussion of factors influencing extraction efficiency, such as DES composition and temperature.
Main Results:
- DESs, especially ionic types like choline-based systems, demonstrate efficacy in natural product extraction.
- Key factors influencing extraction efficiency include hydrogen bonding interactions, viscosity, and temperature.
- DESs facilitate both extraction and subsequent recovery of target compounds.
Conclusions:
- Deep eutectic solvents are a viable and sustainable alternative to traditional solvents and ionic liquids.
- Choline-based ionic DESs show significant potential for efficient natural product isolation.
- Further research into optimizing DES properties can enhance their application in various fields.
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