Therapeutic strategy of central vein perforation accompanied by a mediastinal lesion after catheterization

Chi-Chang Li1, Wei Zhang1, Xing-Jie Wu1

  • 1Cardiovascular Department, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.

Insights

Central vein perforation during catheterization is rare. A novel percutaneous thrombin injection and balloon dilatation technique successfully treated a patient with this complication, offering a new therapeutic option.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Nephrology

Background:

  • Central vein perforation is a rare but serious complication during central venous catheterization, particularly in patients requiring hemodialysis.
  • Chronic kidney disease necessitates long-term hemodialysis, increasing the risk of vascular access procedures and associated complications.

Observation:

  • A 50-year-old woman undergoing hemodialysis experienced central vein injury during attempted double-channel catheter placement.
  • Imaging revealed catheter perforation of the central vein into the mediastinum.

Findings:

  • A multidisciplinary team opted for a minimally invasive approach: percutaneous catheter thrombin injection followed by fluoroscopically guided balloon dilatation.
  • This combined technique successfully sealed the central vein perforation.

Implications:

  • This case highlights a successful endovascular management strategy for central vein perforation, a potentially life-threatening complication.
  • The findings suggest that percutaneous thrombin injection and balloon dilatation can be an effective alternative to surgical repair in select cases.
  • Further research into endovascular techniques for managing central venous injuries is warranted.

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