Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intracellular Signaling Affects Focal Adhesions01:17

Intracellular Signaling Affects Focal Adhesions

3.5K
Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term systolic blood pressure time in target and risk of cardiovascular events in older adults: a secondary analysis of the ASPREE cohort.

American journal of hypertension·2026
Same author

The effect of treating hearing loss with hearing aids on plasma biomarkers of Alzheimer's disease and related dementias.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Heterogeneity of Treatment Effect of Aspirin and Clinically Significant Bleeding in Older Adults.

medRxiv : the preprint server for health sciences·2026
Same author

Resting heart rate and cognitive function in ageing: Insights from a secondary data analysis.

GeroScience·2026
Same author

Cognitive Decline Preceding Incident Cardiovascular Events in Older Adults.

JAMA network open·2026
Same author

Estimation of Detailed Cardiac Doses for Pediatric Radiation Therapy Patients in National Wilms Tumor Study.

International journal of radiation oncology, biology, physics·2026

Related Experiment Video

Updated: Jan 26, 2026

Soil Lysimeter Excavation for Coupled Hydrological, Geochemical, and Microbiological Investigations
10:30

Soil Lysimeter Excavation for Coupled Hydrological, Geochemical, and Microbiological Investigations

Published on: September 11, 2016

11.3K

Focal choroidal excavation: Cause or effect?

Raj C Shah1, Mahesh Gopalakrishnan1, Anubhav Goyal1

  • 1Department of Vitreo-Retina, Giridhar Eye Institute, Ponneth Temple Road, Kadavanthra, Cochin, Kerala, India.

Indian Journal of Ophthalmology
|April 23, 2019
PubMed
Summary
This summary is machine-generated.

Focal choroidal excavation (FCE) can be acquired after choroidal neovascular membrane (CNVM) treatment or pre-existing. This study highlights FCE imaging and its link to the pachychoroid spectrum.

Keywords:
Choroidal neovascular membranefocal choroidal excavationpachychoroid

More Related Videos

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
05:46

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

2.2K
Author Spotlight: Insights and Innovations in Gene Expression Manipulation Techniques for Choroid Plexus Research
04:43

Author Spotlight: Insights and Innovations in Gene Expression Manipulation Techniques for Choroid Plexus Research

Published on: June 16, 2023

1.5K

Related Experiment Videos

Last Updated: Jan 26, 2026

Soil Lysimeter Excavation for Coupled Hydrological, Geochemical, and Microbiological Investigations
10:30

Soil Lysimeter Excavation for Coupled Hydrological, Geochemical, and Microbiological Investigations

Published on: September 11, 2016

11.3K
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
05:46

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

2.2K
Author Spotlight: Insights and Innovations in Gene Expression Manipulation Techniques for Choroid Plexus Research
04:43

Author Spotlight: Insights and Innovations in Gene Expression Manipulation Techniques for Choroid Plexus Research

Published on: June 16, 2023

1.5K

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Diseases

Background:

  • Focal choroidal excavation (FCE) is a rare condition affecting the choroid.
  • Choroidal neovascular membrane (CNVM) is a common cause of vision loss.
  • Spectral-domain optical coherence tomography (SD-OCT) is crucial for visualizing these pathologies.

Observation:

  • This case series presents four patients with FCE.
  • Imaging characteristics of FCE and associated CNVM were analyzed using SD-OCT.
  • FCE was observed as an acquired condition post-CNVM treatment in two patients.
  • FCE was pre-existing in the other two patients.

Findings:

  • SD-OCT revealed distinct imaging features of FCE.
  • The study observed both acquired and pre-existing FCE.
  • A strong association between FCE and the pachychoroid spectrum was reaffirmed.

Implications:

  • Understanding FCE's imaging characteristics aids diagnosis.
  • The findings suggest potential etiopathogenesis pathways for FCE.
  • This reaffirms the link between FCE and pachychoroid diseases, guiding further research.