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Updated: Jan 26, 2026

Three Dimensional Cultures: A Tool To Study Normal Acinar Architecture vs. Malignant Transformation Of Breast Cells
Published on: April 25, 2014
Rare Breast Malignancy Subtypes: A Cytological, Histological, and Immunohistochemical Correlation
Manmeet Kaur1, Kanwardeep Kaur Tiwana1, Nisha Singla1
1Department of Pathology, GGS Medical College and Hospital, Faridkot, Punjab, India.
Background:
Breast malignancies encompass various subtypes which differ in their clinical presentations, outcomes, and response to the treatment regimens. Thus, a proper histological diagnosis and a special mention of the rare histologic subtypes are required to formulate clear recommendations of their treatment protocols.
Materials And Methods:
This is a 1-year retrospective study highlighting the rarely encountered subtypes on the mastectomy specimens received.
Results:
We encountered only 11 rare cases out of the total 153 mastectomy specimens received. The rare subtypes were as follows mucinous cystadenocarcinoma (0.6%), mucinous carcinoma (0.6%), dermatofibrosarcoma protuberans (0.6%), Squamous cell carcinoma (0.6%), papillary carcinoma (2.6%), medullary carcinoma (0.6%), and malignant mesenchymal tumor (1.3%).
Conclusion:
Our data suggest that these variants are distinct clinicopathological entities with a unique hormonal receptor status. Scant information is available on the rare breast tumor subtypes.
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