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Cost Benefit and Utility Decision Analysis of Turbinoplasty with Adenotonsillectomy for Pediatric Sleep-Disordered
Grace Baik1, Scott E Brietzke2
11 Department of Otolaryngology-Head and Neck Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
Insights
Adding turbinoplasty to tonsillectomy/adenoidectomy (T/A) surgery for pediatric obstructive sleep-disordered breathing (oSDB) improves outcomes and is cost-effective. This combined approach offers better utility gains and cost benefits, even with modest improvements.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Health Economics
Background:
- Obstructive sleep-disordered breathing (oSDB) in children often requires surgical intervention.
- Tonsillectomy/adenoidectomy (T/A) is a common treatment, but outcomes can be improved.
- Turbinate hypertrophy is a contributing factor in pediatric oSDB.
Purpose of the Study:
- To assess the utility and cost-effectiveness of adding bilateral inferior turbinoplasty to T/A for pediatric oSDB.
- To determine the impact of turbinoplasty on quality-adjusted life years (QALYs) and overall treatment utility.
- To identify key variables influencing the decision through sensitivity analysis.
Main Methods:
- A cost-utility decision analysis model was developed using hypothetical cohorts.
- Data from published literature and Centers for Medicare and Medicaid databases were utilized.
- Sensitivity analyses were performed to evaluate the impact of key parameters on model outcomes.
Main Results:
- The baseline model favored adding turbinoplasty to T/A, showing higher overall utility (0.8890 vs 0.8875).
- Sensitivity analysis identified treatment success increase as the critical factor; a 3% improvement favored concurrent turbinoplasty.
- The incremental cost-effectiveness ratio (ICER) was $27,333/QALY, below the willingness-to-pay threshold.
Conclusions:
- Adding bilateral inferior turbinoplasty to T/A is beneficial for children with turbinate hypertrophy and pediatric oSDB.
- The combined procedure demonstrates favorable utility gains and cost-benefit advantages.
- Even modest benefits from turbinoplasty support its addition to T/A for improved pediatric oSDB treatment.
Objectives:
Use decision analysis techniques to assess the potential utility gains/losses and costs of adding bilateral inferior turbinoplasty to tonsillectomy/adenoidectomy (T/A) for the treatment of obstructive sleep-disordered breathing (oSDB) in children. Use sensitivity analysis to explore the key variables in the scenario.
Study Design:
Cost-utility decision analysis model.
Setting:
Hypothetical cohort.
Subjects And Methods:
Computer software (TreeAge Software, Williamstown, Massachusetts) was used to construct a decision analysis model. The model included the possibility of postoperative complications and persistent oSDB after surgery. Baseline clinical and quality-adjusted life year (QALY) parameters were estimated using published data. Cost data were estimated from Centers for Medicare and Medicaid 2018 databases ( www.cms.gov ). Sensitivity analyses were completed to assess for key model parameters.
Results:
The utility analysis of the baseline model favored the addition of turbinoplasty (0.8890 vs 0.8875 overall utility) assuming turbinate hypertrophy was present. Sensitivity analysis indicated the treatment success increase (%) provided by concurrent turbinoplasty was the key parameter in the model. A treatment success increase of 3% of turbinoplasty was the threshold where concurrent turbinoplasty was favored over T/A alone. The incremental cost-effectiveness ratio (ICER) of $27,333/QALY for the baseline model was favorable to the willingness-to-pay threshold of $50,000 to $100,000/QALY for industrialized nations.
Conclusions:
The addition of turbinoplasty for children with turbinate hypertrophy to T/A for the treatment of pediatric oSDB is beneficial from both a utility and cost-benefit analysis standpoint even if the benefits of turbinoplasty are relatively modest.
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